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To be updated
- Our Comment article (Chuang as the corresponding author) has been accepted in Nature Reviews Materials.
- Our Review article (Chuang as the corresponding author) has been accepted in Nano Letters.
Featured Publications
- Chuang Liu, Xiangang Huang, Kok-Siong Chen, Sihan Xiong, Alexey V Yaremenko, Xueyan Zhen, Xinru You, Filippo Rossignoli, Yi Tang, Seyoung Koo, Wei Chen, Na Kong, Tian Xie, Khalid Shah, Wei Tao*. Systemic reprogramming of tumour immunity via IL-10-mRNA nanoparticles. Nature Nanotechnology (2025).
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Chuang Liu#, Qiangqiang Shi#, Xiangang Huang, Seyoung Koo, Na Kong*, Wei Tao*. mRNA-based cancer therapeutics. Nature Reviews Cancer (2023), 23, 526–543.
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Chuang Liu#, Alexey V. Yaremenko#, Xiaolong Li#, Xinru You, Xiaoyu Zhu, Nuo Liu, Wei Chen, Na Kong, Tian Xie, Gaurav D. Gaiha*, Robert Langer, and Wei Tao*. mRNA technology for the prevention and treatment of HIV-1 infection. Nature Reviews Bioengineering (2025)
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Chuang Liu*. mRNA-based enzyme replacement for propionic acidaemia. Nature Reviews Endocrinology (2025), 21, 526.
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Sihan Xiong, Chuang Liu*. Core mission: mRNA endosomal escape. Nature Reviews Chemistry (2025), 9, 433.
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Sihan Xiong, Khalid Shah*, Chuang Liu*. A zwitterionic twist. Nature Reviews Chemistry (2024), 8, 721.
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Chuang Liu, Khalid Shah*. Taming CAR T cell therapy toxicity. Nature Materials (2023), 22, 1444–1445.
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Xiangang Huang#, Chuang Liu#, Na Kong, Yufen Xiao, Arif Yurdagul, Ira Tabas, Wei Tao*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols (2022), 17, 748–780.
Selected Publications by Years
2025
- Chuang Liu#, Alexey V. Yaremenko#, Xiaolong Li#, Xinru You, Xiaoyu Zhu, Nuo Liu, Wei Chen, Na Kong, Tian Xie, Gaurav D. Gaiha*, Robert Langer, and Wei Tao*. mRNA technology for the prevention and treatment of HIV-1 infection. Nature Reviews Bioengineering (2025)
- Chuang Liu, Xiangang Huang, Kok-Siong Chen, Sihan Xiong, Alexey V Yaremenko, Xueyan Zhen, Xinru You, Filippo Rossignoli, Yi Tang, Seyoung Koo, Wei Chen, Na Kong, Tian Xie, Khalid Shah, Wei Tao*. Systemic reprogramming of tumour immunity via IL-10-mRNA nanoparticles. Nature Nanotechnology (2025). đFull text: rdcu.be/eAcNi. đHighlighted byăMin.NewsăăBioon.comă
- Chuang Liu*. mRNA-based enzyme replacement for propionic acidaemia. Nature Reviews Endocrinology (2025), 21, 526.
- Sihan Xiong, Chuang Liu*. Core mission: mRNA endosomal escape. Nature Reviews Chemistry (2025), 9, 433.
- Xiangang Huang, Chuang Liu, Shonit Nair Sharma, Xinru You, Shuying Chen, Yongjiang Li, Hai-Jun Liu, Bin Liu, Qimanguli Saiding, Wei Chen, Yuhan Lee, Na Kong, Reza Abdi, Wei Tao*. Oral delivery of liquid mRNA therapeutics by an engineered capsule for treatment of preclinical intestinal disease. Science Translational Medicine (2025), 17,eadu1493.
2024
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Nadezhda A Pechnikova*, Amalia Aggeli, Anastasiia A Latypova, Aleksandra V Iaremenko, Kalliopi Domvri, Ilya V Zubarev, Chuang Liu*, Alexey V Yaremenko*. Implantable Biomaterials for Cancer Immunotherapies. Advanced Functional Materials (2025), 35, 2416813.
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Sihan Xiong, Khalid Shah*, Chuang Liu*. A zwitterionic twist. Nature Reviews Chemistry (2024), 8, 721.
2023
- Chuang Liu, Khalid Shah*. Taming CAR T cell therapy toxicity. Nature Materials (2023), 22, 1444–1445.
- Chuang Liu#, Qiangqiang Shi#, Xiangang Huang, Seyoung Koo, Na Kong*, Wei Tao*. mRNA-based cancer therapeutics. Nature Reviews Cancer (2023), 23, 526–543. đăHighlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection; Web of Science Hot | Highly Cited Paperă
- Wei Chen#, Yongjiang Li#, Chuang Liu#, Yong Kang, Duotian Qin, Shuying Chen, Jun Zhou, HaiâJun Liu, Bijan Emiliano Ferdows, Dylan Neal Patel, Xiangang Huang, Seyoung Koo, Na Kong, Xiaoyuan Ji, Yihai Cao, Wei Tao*, Tian Xie*. In situ Engineering of TumorâAssociated Macrophages via a NanodrugâDeliveringâDrug (βâElemene@Stanene) Strategy for Enhanced Cancer ChemoâImmunotherapy. Angewandte Chemie International Edition (2023), 62, e202308413.
2022
- Xiangang Huang#, Chuang Liu#, Na Kong, Yufen Xiao, Arif Yurdagul, Ira Tabas, Wei Tao*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols (2022), 17, 748–780.
- Zhongyang Zhang#, Jun Zhou#, Chuang Liu#, Jiaming Zhang, Yo Shibata, Na Kong, Claudia Corbo*, Mitchel B Harris*, Wei Tao*. Emerging biomimetic nanotechnology in orthopedic diseases: progress, challenges, and opportunities. Trends in Chemistry (2022), 4, 5, 420-436.
2021
- Wen Pan#, Chuang Liu#, Yunhui Li*, Yang Yang, Wenliang Li, Chan Feng*, Leijiao Li*. Ultrathin tellurium nanosheets for simultaneous cancer thermo-chemotherapy. Bioactive Materials (2021), 13, 96-104.
- Chuang Liu#, Shan Sun#, Qiang Feng#, Gongwei Wu, Yiting Wu, Na Kong, Zhangsen Yu, Junlie Yao, Xingcai Zhang, Wei Chen, Zhongmin Tang, Yufen Xiao, Xiangang Huang, Aman Lv, Chenyang Yao, Haibo Cheng, Aiguo Wu*, Tian Xie*, Wei Tao*. Arsenene Nanodots with Selective Killing Effects and their LowâDose Combination with ßâElemene for Cancer Therapy. Advanced Materials (2021), 33, 2102054.
- Wei Chen#, Chuang Liu#, Xiaoyuan Ji, John Joseph, Zhongmin Tang, Jiang Ouyang, Yufen Xiao, Na Kong, Nitin Joshi, Omid C Farokhzad*, Wei Tao*, Tian Xie*. StaneneâBased Nanosheets for βâElemene Delivery and UltrasoundâMediated Combination Cancer Therapy. Angewandte Chemie International Edition (2021), 60, 7155.
- Chuang Liu#, Jinwoo Shin#, Subin Son#, Youmi Choe#, Nika Farokhzad, Zhongmin Tang, Yufen Xiao, Na Kong*, Tian Xie*, Jong Seung Kim*, Wei Tao*. Pnictogens in medicinal chemistry: evolution from erstwhile drugs to emerging layered photonic nanomedicine. Chemical Society Reviews (2021), 50, 2260-2279.
2020
- Jielai Yang#, Xingcai Zhang#, Chuang Liu#, Zhen Wang, Lianfu Deng, Chan Feng, Wei Tao*, Xiangyang Xu*, Wenguo Cui*. Biologically Modified Nanoparticles as Theranostic Bionanomaterials. Progress in Materials Science (2020), 118, 100768.
- Chuang Liu#, Hyeong Seok Kim#, Miae Won#, Eugeine Jung, and Jong Seung Kim*. Navigating 2D Monoelemental Materials (Xenes) for Cancer Nanomedicine. Matter (2020), 3, 1, 12-13.
- Chuang Liu#, Junlie Yao#, Jiapeng Hu#, Ozioma Udochukwu Akakuru, Shan Sun, Tianxiang Chen*, Aiguo Wu*. Navigating nMOF-mediated enzymatic reactions for catalytic tumor-specific therapy. Materials Horizons (2020), 7, 3176-3186.
2019
- Chuang Liu, Jie Xing, Ozioma Udochukwu Akakuru, Lijia Luo, Shan Sun, Ruifen Zou, Zhangsen Yu, Qianlan Fang, Aiguo Wu*. Nanozymes-engineered metal–organic frameworks for catalytic cascades-enhanced synergistic cancer therapy. Nano Letters (2019), 19, 8, 5674–5682.
2018
- Luyun Zhang#, Chuang Liu#, Yang Gao, Zihou Li, Jie Xing, Wenzhi Ren, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*, Leyong Zeng*. ZD2-Engineered Gold Nanostar@Metal-Organic Framework Nanoprobes for T1-Weighted Magnetic Resonance Imaging and Photothermal Therapy Specifically Toward Triple-Negative Breast Cancer. Advanced Healthcare Materials (2018), 7, 1801144.
- Chuang Liu, Lijia Luo, Leyong Zeng, Jie Xing, Yuanzhi Xia, Shan Sun, Luyun Zhang, Zhe Yu, Junlie Yao, Zhangsen Yu, Ozioma Udochukwu Akakuru, Madiha Saeed, Aiguo Wu*. Porous Gold Nanoshells on Functional NH2-MOFs: Facile Synthesis and Designable Platforms for Cancer Multiple Therapy. Small (2018),14, 1801851.